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LARTEM
24 TABLETS
 
L-Artem tablets are indicated for the treatment of P. falciparum malaria cases resistant to both chloroquine and sulphadoxine pyrimethamine combination.
Price Range:
KES 0 - KES 0
 
Mechanism of Action Artemether is concentrated in the food vacuole. It interacts with haem, blocking conversion to haemozoin, destroying existing haemozoin and releasing haem and a cluster of free radicals into the parasite. Lumefantrine is thought to interfere with the haem polymerisation process. Both Artemether and Lumefantrine have a secondary action involving inhibition of nucleic acid and protein synthesis within the malarial parasite. Artemether is fast acting drug with a short half-life. Lumefantrine acts slowly and has a longer half-life. Side Effects Headache, dizziness, sleep disorder, abdominal pain, anorexia, diarrhoea, vomiting, nausea, palpitation, cough, arthralgia, myalgia, pruritus, rash, asthenia and fatigue. Somnolence, involuntary muscle contractions, paraesthesia, hypoaesthesia, abnormal gait, ataxia.
 
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Ansell Pharmaceuticals Mombasa
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Pha-Medic Pharmaceuticals
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HealthPlus Chemist
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